If your weight, blood pressure, cholesterol or blood sugar levels fluctuate, you may have a higher risk of heart attack, stroke and premature death than people with more steady readings, new research suggests.

According to the study, during nearly six years of follow-up, men and women whose readings changed the most were 127 percent more likely to die, 43 percent more likely to have a heart attack and 41 percent more likely to have a stroke, compared with those whose readings remained stable.

“Variability in metabolic parameters may have a role in predicting mortality and cardiovascular outcomes,” said lead study author Dr. Seung-Hwan Lee, a professor of endocrinology at the College of Medicine at Catholic University of Korea in Seoul.

The report was published online Oct. 1 in the journal Circulation.

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