He is trailing Democratic presidential nominee Joe Biden in most national and battleground state polls, making Thursday night’s debate the incumbent’s last best chance to change the trajectory of a race that, with less than two weeks to run, appears to favor the challenger.

After an initial match up that quickly descended into a glorified shouting match, with Trump repeatedly interrupting Biden and running roughshod over the moderator, the second debate, scheduled for last week, was canceled after the President tested positive for the coronavirus and subsequently refused to take part in a virtual meeting.

This time, the Commission on Presidential Debates has given the green light to an in-person face-off, but with one unprecedented change: The candidates will have their microphones cut off while their opponents respond to the first question of each of the debate’s six segments.

The topics slated for discussion over 90 uninterrupted minutes, beginning at 9 p.m. ET, include “Fighting COVID-19,” “American Families,” “Race in America,” “Climate Change,” “National Security” and “Leadership.”

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